Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.85 |
| ▸ | MEN1 | O00255 | 3/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | TOP1 | P11387 | 1/20 | 0.57 |
| ▸ | TOP2A | P11388 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Difloxacin SCHEMBL29695838 | 0.92 | LMNA (1.00) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| Difloxacin SCHEMBL148765 | 0.92 | LMNA (1.00) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| Difloxacin SCHEMBL203110 | 0.91 | LMNA (0.98) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9787515 | 0.91 | LMNA (0.86) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10531040 | 0.91 | LMNA (0.86) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| Difloxacin SCHEMBL27973383 | 0.90 | LMNA (0.96) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9047088 | 0.88 | MEN1 (0.67) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10861606 | 0.88 | LMNA (0.82) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9044286 | 0.88 | ALDH1A1 (0.83) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10776491 | 0.87 | LMNA (0.80) | LMNAMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422485-B1 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1996-04-03 | — | — | EP | claimed |
| EP-0422485-B1 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1996-04-03 | — | — | EP | disclosed |