Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.49 |
| ▸ | GUSB | P08236 | 1/20 | 0.48 |
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718869 | 0.82 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL28027631 | 0.79 | TNKS (0.54) | ALDH1A1SMN1; SMN2GAAKDM4EHPGD | |
| SCHEMBL9044504 | 0.78 | GUSB (0.56) | ALDH1A1GAAMAPTAMY1AFGFR1 | |
| SCHEMBL9045167 | 0.77 | PARP1 (0.60) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL24834182 | 0.77 | DCPS (0.47) | ALDH1A1KDM4EMAPTHPGDNPC1 | |
| SCHEMBL31723877 | 0.77 | DCPS (0.47) | ALDH1A1KDM4EMAPTHPGDNPC1 | |
| SCHEMBL8648025 | 0.75 | PARP1 (0.67) | AMY1AFGFR1FGFR2GUSBPDE5A | |
| SCHEMBL22323763 | 0.74 | PDE5A (0.52) | ALDH1A1GAAKDM4EGLAHSD17B10 | |
| SCHEMBL5202015 | 0.74 | RPS6KA2 (0.45) | MAPTNPC1RAB9AAMY1AGUSB | |
| SCHEMBL27461815 | 0.73 | KDM4E (0.54) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700906-A1 | Heterocyclic derivatives of N-phenylamides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-13 | — | — | EP | disclosed |
| US-5496826-A | ANTICONVULSANTS, MELATONERGIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-05 | — | — | US | disclosed |