Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043647 | 0.91 | MAPT (0.32) | ALDH1A1L3MBTL1HTTHPGDHCRTR1 | |
| SCHEMBL9045620 | 0.87 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1HTTHPGDMAPT | |
| SCHEMBL9044517 | 0.84 | ADORA2A (0.30) | ALDH1A1L3MBTL1POLBADORA2AADORA2B | |
| SCHEMBL9044500 | 0.83 | ADORA2A (0.30) | HTTMAPTADORA2AADORA2B | |
| SCHEMBL9044711 | 0.81 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1HTTMAPTPOLB | |
| SCHEMBL9044002 | 0.80 | POLB (0.36) | ALDH1A1L3MBTL1HPGDMAPTPOLB | |
| SCHEMBL9044597 | 0.76 | HCRTR1 (0.35) | ALDH1A1L3MBTL1HTTHPGDHCRTR1 | |
| SCHEMBL9044240 | 0.75 | HCRTR1 (0.36) | ALDH1A1L3MBTL1HTTHPGDHCRTR1 | |
| SCHEMBL8987728 | 0.75 | POLB (0.38) | ALDH1A1L3MBTL1HTTHPGDHCRTR1 | |
| SCHEMBL9043112 | 0.75 | ADORA2A (0.37) | ALDH1A1L3MBTL1HTTHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358609-B1 | Parasiticide compounds | CIBA GEIGY AG (CH) | 1996-07-24 | — | — | EP | claimed |
| EP-0358609-A2 | Parasiticide compounds | CIBA-GEIGY AG (CH) | 1990-03-14 | — | — | EP | claimed |
| EP-0358609-B1 | Parasiticide compounds | CIBA GEIGY AG (CH) | 1996-07-24 | — | — | EP | disclosed |
| EP-0358609-A2 | Parasiticide compounds | CIBA-GEIGY AG (CH) | 1990-03-14 | — | — | EP | disclosed |