Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 12/20 | 0.44 |
| ▸ | HTR1B | P28222 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9048457 | 0.91 | HTR1D (0.41) | HTR1DHTR1BMAPTBLMNPSR1 | |
| Oxalic Acid SCHEMBL9046695 | 0.91 | DRD2 (0.43) | HTR1DHTR1BMAPTBLMNPSR1 | |
| Oxalic Acid SCHEMBL9048375 | 0.90 | MAPT (0.56) | HTR1DHTR1BMAPTBLMNPSR1 | |
| Oxalic Acid SCHEMBL9046888 | 0.89 | CCR2 (0.44) | HTR1DHTR1BCCR2OPRM1OPRK1 | |
| Oxalic Acid SCHEMBL9048417 | 0.88 | SLC6A4 (0.55) | CCR2HTR1ADRD2 | |
| Oxalic Acid SCHEMBL7859768 | 0.84 | OPRM1 (0.48) | CCR2OPRM1OPRK1OPRL1DRD2 | |
| SCHEMBL8111835 | 0.83 | OPRM1 (0.57) | HTR1DOPRM1OPRK1OPRL1HTR1A | |
| Hydrochloric Acid SCHEMBL7009951 | 0.82 | OPRM1 (0.56) | HTR1DOPRM1OPRK1OPRL1HTR1A | |
| Hydrochloric Acid SCHEMBL9045292 | 0.82 | OPRM1 (0.60) | HTR1DHTR1BOPRM1OPRK1OPRL1 | |
| Oxalic Acid SCHEMBL9044366 | 0.81 | OPRM1 (0.51) | HTR1DCCR2OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708102-A1 | 5-HT1F agonists for the treatment of migraine | ELI LILLY AND COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |