Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280288 | 0.83 | PKM (0.58) | IDO1CYP3A4MAPTPOLBCA2 | |
| SCHEMBL1792873 | 0.79 | IDO1 (0.60) | IDO1CYP3A4MAPTPOLBCA12 | |
| SCHEMBL11100773 | 0.77 | ALDH1A1 (0.41) | CYP3A4MAPTTDP1GAAHPGD | |
| Hydrochloric Acid SCHEMBL7340226 | 0.77 | MAPT (0.62) | IDO1CYP3A4MAPTPOLBCA12 | |
| SCHEMBL8339124 | 0.76 | NSD2 (0.36) | POLBNSD2KMT2ALMNASIGMAR1 | |
| SCHEMBL31125781 | 0.76 | FDPS (0.41) | IDO1CYP3A4MAPTPOLBNSD2 | |
| SCHEMBL16584664 | 0.75 | ALDH1A1 (0.56) | IDO1CYP3A4KMT2AMEN1TDP1 | |
| SCHEMBL2129001 | 0.75 | TSHR (0.52) | CYP3A4CA12CA2HPGDL3MBTL1 | |
| SCHEMBL28354630 | 0.73 | HRAS (0.49) | IDO1MAPTPOLBNSD2GAA | |
| SCHEMBL542553 | 0.73 | HTR2A (0.56) | CYP3A4POLBKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514917-B1 | Process for and 2-(cyanoimino)-quinazoline derivatives useful as intermediates in the preparation of 6,7-di-(chloro)-1,5-di(hydro)-imidazo-[2,1-b]quinazolin-2[3H]-one and process for preparing the 2-(cyanoimino)-quinazoline derivatives | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1996-12-27 | — | — | EP | disclosed |