Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21514726 | 0.89 | TDP1 (0.61) | TDP1ALDH1A1CYP3A4CA2TAS1R3 | |
| SCHEMBL63068 | 0.87 | TDP1 (0.67) | TDP1ALDH1A1CYP3A4CA2TAS1R3 | |
| SCHEMBL126604 | 0.86 | TDP1 (0.56) | TDP1ALDH1A1CYP3A4CA2TAS1R3 | |
| SCHEMBL5198950 | 0.86 | TDP1 (0.56) | TDP1ALDH1A1CYP3A4CA2TAS1R3 | |
| SCHEMBL17627791 | 0.86 | TDP1 (0.56) | TDP1ALDH1A1CYP3A4CA2TAS1R3 | |
| SCHEMBL2531606 | 0.85 | TDP1 (0.65) | TDP1ALDH1A1CYP3A4CA2TAS1R3 | |
| SCHEMBL8436026 | 0.84 | TDP1 (0.64) | TDP1ALDH1A1CYP3A4CA2TAS1R3 | |
| SCHEMBL8436027 | 0.84 | TDP1 (0.64) | TDP1ALDH1A1CYP3A4CA2TAS1R3 | |
| Octinoxate SCHEMBL30081040 | 0.84 | TDP1 (0.79) | TDP1ALDH1A1CYP3A4CA2TAS1R3 | |
| SCHEMBL20049917 | 0.83 | TDP1 (0.62) | TDP1ALDH1A1CYP3A4CA2TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10899919-B2 | 4- and 5-substituted 1,2,3-triazole, and regioisomer mixtures thereof, modified polymers | ISP INVESTMENTS LLC (US) | 2021-01-26 | — | — | US | disclosed |
| US-10087273-B2 | Multifunctional polymers | ISP INVESTMENTS LLC (US) | 2018-10-02 | — | — | US | disclosed |
| US-10081757-B2 | Shale swelling inhibitors | ISP INVESTMENTS LLC (US) | 2018-09-25 | — | — | US | disclosed |
| US-9505862-B2 | Polymers containing an acetoacetate moiety | ISP INVESTMENTS LLC (US) | 2016-11-29 | — | — | US | disclosed |
| US-9464151-B2 | Lactamic polymer containing an acetoacetate moiety | ISP INVESTMENTS LLC (US) | 2016-10-11 | — | — | US | disclosed |
| US-20160152814-A1 | 4- AND 5-SUBSTITUTED 1,2,3-TRIAZOLE, AND REGIOISOMER MIXTURES THEREOF, MODIFIED POLYMERS | ISP INVESTMENTS INC. (US) | 2016-06-02 | — | — | US | disclosed |
| US-20150344767-A1 | SHALE SWELLING INHIBITORS | ISP INVESTMENTS INC. (US) | 2015-12-03 | — | — | US | disclosed |
| US-20150051352-A1 | MULTI-FUNCTIONAL GRAFTED POLYMERS | ISP INVESTMENTS INC. | 2015-02-19 | — | — | US | disclosed |
| US-20150044161-A1 | MULTIFUNCTIONAL POLYMERS | ISP INVESTMENTS INC. (US) | 2015-02-12 | — | — | US | disclosed |
| US-8946367-B2 | Polymerizable carbamate and thiocarbamate compounds, polymers derived from them, and compositions thereof | ISP INVESTMENTS INC. (US) | 2015-02-03 | — | — | US | disclosed |
| US-20150005465-A1 | POLYMERS CONTAINING AN ACETOACETATE MOIETY | AVOCA LLC | 2015-01-01 | — | — | US | disclosed |
| US-20140296441-A1 | LACTAMIC POLYMER CONTAINING AN ACETOACETATE MOIETY | ISP INVESTMENTS INC (US) | 2014-10-02 | — | — | US | disclosed |
| US-20130090443-A1 | POLYMERIZABLE CARBAMATE AND THIOCARBAMATE COMPOUNDS, POLYMERS DERIVED FROM THEM, AND COMPOSITIONS THEREOF | ISP INVESTMENTS INC. (US) | 2013-04-11 | — | — | US | disclosed |
| WO-2011163317-A2 | POLYMERIZABLE CARBAMATE AND THIOCARBAMATE COMPOUNDS, POLYMERS DERIVED FROM THEM, AND COMPOSITIONS THEREOF | ISP INVESTMENTS INC. (US) | 2011-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090443-A1 | POLYMERIZABLE CARBAMATE AND THIOCARBAMATE COMPOUNDS, POLYMERS DERIVED FROM THEM, AND COMPOSITIONS THEREOF | CUTA, CTH, ACOT7 | TDP1 1084/4885ALDH1A1 1560/4885CYP3A4 1446/4885 |
| US-10899919-B2 | 4- and 5-substituted 1,2,3-triazole, and regioisomer mixtures thereof, modified polymers | MGAT3, MYOC, MLEC | TDP1 1207/4885ALDH1A1 1170/4885CYP3A4 115/4885 |
| US-20150051352-A1 | MULTI-FUNCTIONAL GRAFTED POLYMERS | PAICS, ODC1, GANC | TDP1 4068/4885ALDH1A1 744/4885CYP3A4 3794/4885 |
| US-20150044161-A1 | MULTIFUNCTIONAL POLYMERS | PUF60, PARG, PARN | TDP1 2910/4885ALDH1A1 3833/4885CYP3A4 4729/4885 |
| US-20160152814-A1 | 4- AND 5-SUBSTITUTED 1,2,3-TRIAZOLE, AND REGIOISOMER MIXTURES THEREOF, MODIFIED POLYMERS | MGAT3, MYOC, MLEC | TDP1 1207/4885ALDH1A1 1170/4885CYP3A4 115/4885 |
| US-10087273-B2 | Multifunctional polymers | PUF60, PARG, PARN | TDP1 2910/4885ALDH1A1 3833/4885CYP3A4 4729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.