Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 2/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 2/20 | 1.00 |
| ▸ | PDPK1 | O15530 | 1/20 | 1.00 |
| ▸ | PRKCA | P17252 | 1/20 | 1.00 |
| ▸ | BACE1 | P56817 | 1/20 | 1.00 |
| ▸ | PRKCQ | Q04759 | 1/20 | 1.00 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.81 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.81 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.81 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.81 |
| ▸ | MAOA | P21397 | 1/20 | 0.81 |
| ▸ | PDE5A | O76074 | 1/20 | 0.81 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.75 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.69 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoxanthohumol SCHEMBL30033683 | 1.00 | ESR1 (1.00) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| Isoxanthohumol SCHEMBL30034254 | 1.00 | ESR1 (1.00) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| Isoxanthohumol SCHEMBL14092988 | 1.00 | ESR1 (1.00) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| Isoxanthohumol SCHEMBL29743582 | 1.00 | ESR1 (1.00) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| Munduleaflavanone B SCHEMBL14049994 | 0.93 | ESR1 (0.87) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| 7-O-Methylisoxanthohumol SCHEMBL29929829 | 0.93 | ESR1 (0.87) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| SCHEMBL30630212 | 0.92 | ESR1 (0.85) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| SCHEMBL14982147 | 0.91 | ESR1 (0.84) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| SCHEMBL26113090 | 0.91 | ESR1 (0.82) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| Sophoraflavanone B SCHEMBL1171435 | 0.90 | ESR1 (1.00) | ESR1AKR1B10AKR1B1PDPK1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240315965-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2024-09-26 | — | — | US | claimed |
| WO-2022182527-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2022-09-01 | — | — | WO | claimed |
| EP-1893173-B1 | AMINO-OXO-INDOLE-YLIDENE COMPOUNDS FOR USE IN TREATING SCALP SKIN ITCHING | UNILEVER PLC (GB) | 2010-10-06 | — | — | EP | claimed |
| US-20080207928-A1 | Hair and/or Scalp Care Compositions Incorporating Flavonoid Compounds | CONOPCO, INC. D/B/A UNILEVER | 2008-08-28 | — | — | US | claimed |
| US-20250221944-A1 | COMPOSITION FOR PREVENTING OR TREATING MULTIPLE MYELOMA COMPRISING NOVEL CHROMANON COMPOUND AS ACTIVE INGREDIENT | KBLUEBIO INC (KR) | 2025-07-10 | — | — | US | disclosed |
| EP-4506328-A1 | COMPOSITION FOR PREVENTING OR TREATING MULTIPLE MYELOMA COMPRISING NOVEL CHROMANON COMPOUND AS ACTIVE INGREDIENT | KBlueBio Inc (KR) | 2025-02-12 | — | — | EP | disclosed |
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |
| WO-2024010471-A2 | METHOD OF ISOLATION AND PURIFICATION OF XANTHOHUMOL | INNOX Sp. z o.o. (PL) | 2024-01-11 | — | — | WO | disclosed |
| WO-2023195791-A1 | COMPOSITION FOR PREVENTING OR TREATING MULTIPLE MYELOMA COMPRISING NOVEL CHROMANON COMPOUND AS ACTIVE INGREDIENT | 케이블루바이오 주식회사 | 2023-10-12 | — | — | WO | disclosed |
| US-20230190852-A1 | COMPOSITIONS AND METHODS FOR JOINT HEALTH | UNIGEN, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230190852-A1 | COMPOSITIONS AND METHODS FOR JOINT HEALTH | UNIGEN, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| CN-115944622-A | Isoluplin compound and application and pharmaceutical composition thereof | 香港中文大学（深圳） | 2023-04-11 | — | — | CN | disclosed |
| EP-2082726-A2 | Hair and/or scalp care compositions incorporating flavonoid compounds | Unilever PLC (GB) | 2009-07-29 | — | — | EP | disclosed |
| US-20090130724-A1 | Enzymatic Demethylation of Flavonoids | UNIVERSITEIT GENT (BE) | 2009-05-21 | — | — | US | disclosed |
| US-20090130724-A1 | Enzymatic Demethylation of Flavonoids | UNIVERSITEIT GENT (BE) | 2009-05-21 | — | — | US | disclosed |
| WO-2009026206-A1 | METHOD FOR SYNTHESIZING XANTHOHUMOL | UNIVERSITY OF TOLEDO (US) | 2009-02-26 | — | — | WO | disclosed |
| EP-1869200-B1 | ENZYMATIC DEMETHYLATION OF FLAVONOIDS | UNIV GENT (BE) | 2008-09-03 | — | — | EP | disclosed |
| EP-1869200-B1 | ENZYMATIC DEMETHYLATION OF FLAVONOIDS | UNIV GENT (BE) | 2008-09-03 | — | — | EP | disclosed |
| EP-1869200-A1 | ENZYMATIC DEMETHYLATION OF FLAVONOIDS | UNIVERSITEIT GENT (BE) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006099699-A1 | ENZYMATIC DEMETHYLATION OF FLAVONOIDS | UNIVERSITEIT GENT (BE) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207928-A1 | Hair and/or Scalp Care Compositions Incorporating Flavonoid Compounds | POLR1C, F3, AKR1C3 | ESR1 1167/4885AKR1B10 119/4885AKR1B1 35/4885 |
| US-20230190852-A1 | COMPOSITIONS AND METHODS FOR JOINT HEALTH | PTGES, PTGES3, PTGES2 | ESR1 3736/4885AKR1B10 2429/4885AKR1B1 2475/4885 |
| US-20250221944-A1 | COMPOSITION FOR PREVENTING OR TREATING MULTIPLE MYELOMA COMPRISING NOVEL CHROMANON COMPOUND AS ACTIVE INGREDIENT | MCL1, CRBN, BCL3 | ESR1 3399/4885AKR1B10 799/4885AKR1B1 1721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.