Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 2/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 2/20 | 1.00 |
| ▸ | PDPK1 | O15530 | 1/20 | 1.00 |
| ▸ | PRKCA | P17252 | 1/20 | 1.00 |
| ▸ | BACE1 | P56817 | 1/20 | 1.00 |
| ▸ | PRKCQ | Q04759 | 1/20 | 1.00 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.81 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.81 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.81 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.81 |
| ▸ | MAOA | P21397 | 1/20 | 0.81 |
| ▸ | PDE5A | O76074 | 1/20 | 0.81 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.75 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.69 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoxanthohumol SCHEMBL30033683 | 1.00 | ESR1 (1.00) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| Isoxanthohumol SCHEMBL30034254 | 1.00 | ESR1 (1.00) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| Isoxanthohumol SCHEMBL14092988 | 1.00 | ESR1 (1.00) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| Isoxanthohumol SCHEMBL904557 | 1.00 | ESR1 (1.00) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| Munduleaflavanone B SCHEMBL14049994 | 0.93 | ESR1 (0.87) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| 7-O-Methylisoxanthohumol SCHEMBL29929829 | 0.93 | ESR1 (0.87) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| SCHEMBL30630212 | 0.92 | ESR1 (0.85) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| SCHEMBL14982147 | 0.91 | ESR1 (0.84) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| SCHEMBL26113090 | 0.91 | ESR1 (0.82) | ESR1AKR1B10AKR1B1PDPK1PRKCA | |
| Sophoraflavanone B SCHEMBL1171435 | 0.90 | ESR1 (1.00) | ESR1AKR1B10AKR1B1PDPK1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112641947-B | Screening target spot, application and screening method of anti-tumor drug | 沈阳福洋医药科技有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-117551068-B | Isofluoside alcohol amine copolymer, preparation method and antibacterial application thereof | University of South China (CN) | 2026-05-26 | — | — | CN | disclosed |
| US-20250009620-A1 | Oral Care Compositions Comprising Hops Beta Acids | THE PROCTER & GAMBLE COMPANY | 2025-01-09 | — | — | US | disclosed |
| WO-2024163921-A2 | METHODS AND COMPOSITIONS FOR ALTERING METABOLITES IN HOP PLANTS | IMPELLO BIOSCIENCES, INC. (US) | 2024-08-08 | — | — | WO | disclosed |
| US-12042523-B2 | Compositions and methods for managing or improving bone disorders, joint disorders, cartilage disorders, or a combination thereof | UNIGEN, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| US-20240239732-A1 | A METHOD FOR SYNTHESIZING XANTHOHUMOL | Proxn Sp. Z o.o. (PL) | 2024-07-18 | — | — | US | disclosed |
| EP-2984072-B1 | SYNTHETIC ANALOGUES OF XANTHOHUMOL | UNIV PISA (IT) | 2024-05-29 | — | — | EP | disclosed |
| US-20240118263-A1 | TARGET FOR SCREENING ANTI-TUMOR DRUG, USE THEREOF AND SCREENING METHOD THEREFOR | SHENYANG FUYANG PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2024-04-11 | — | — | US | disclosed |
| CN-117551068-A | Isofluoside alcohol amine copolymer, preparation method and antibacterial application thereof | 南华大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-117321028-A | Method for synthesizing xanthohumol | 普罗克森有限责任公司 | 2023-12-29 | — | — | CN | disclosed |
| EP-4153558-B1 | A METHOD FOR SYNTHESIZING XANTHOHUMOL | PROXN SP Z O O (PL) | 2023-08-02 | — | — | EP | disclosed |
| US-20230201295-A1 | Compositions and Methods for Managing or Improving Bone Disorders, Joint Disorders, Cartilage Disorders, or a Combination Thereof | UNIGEN, INC. (US) | 2023-06-29 | — | — | US | disclosed |
| EP-3991572-A4 | ISOXANTHOHUMOL-CONTAINING COMPOSITION, XANTHOHUMOL-CONTAINING COMPOSITION, METHODS FOR PRODUCING SAME, AND METHODS FOR REDUCING BITTERNESS THEREOF | Suntory Holdings Limited (JP) | 2023-06-28 | — | — | EP | disclosed |
| US-20230190852-A1 | COMPOSITIONS AND METHODS FOR JOINT HEALTH | UNIGEN, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| EP-4153558-A1 | A METHOD FOR SYNTHESIZING XANTHOHUMOL | Proxn Sp. Z o.o. (PL) | 2023-03-29 | — | — | EP | disclosed |
| US-11554153-B2 | Compositions and methods for managing or improving bone disorders, joint disorders, cartilage disorders, or a combination thereof | UNIGEN, INC. (US) | 2023-01-17 | — | — | US | disclosed |
| WO-2022233428-A1 | A METHOD FOR SYNTHESIZING XANTHOHUMOL | DERMOTECH BEAUTY SP. Z O.O. (PL) | 2022-11-10 | — | — | WO | disclosed |
| CN-115068574-A | Compositions and methods for joint health | 尤妮金公司 | 2022-09-20 | — | — | CN | disclosed |
| EP-3991572-A1 | ISOXANTHOHUMOL-CONTAINING COMPOSITION, XANTHOHUMOL-CONTAINING COMPOSITION, METHODS FOR PRODUCING SAME, AND METHODS FOR REDUCING BITTERNESS THEREOF | Suntory Holdings Limited (JP) | 2022-05-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240118263-A1 | TARGET FOR SCREENING ANTI-TUMOR DRUG, USE THEREOF AND SCREENING METHOD THEREFOR | SELENOI, GSTK1, GSTP1 | ESR1 2690/4885AKR1B10 2130/4885AKR1B1 1722/4885 |
| US-12042523-B2 | Compositions and methods for managing or improving bone disorders, joint disorders, cartilage disorders, or a combination thereof | MATR3, ACACA, COL2A1 | ESR1 4659/4885AKR1B10 1225/4885AKR1B1 1234/4885 |
| US-11554153-B2 | Compositions and methods for managing or improving bone disorders, joint disorders, cartilage disorders, or a combination thereof | MATR3, ACACA, COL2A1 | ESR1 4659/4885AKR1B10 1225/4885AKR1B1 1234/4885 |
| US-20240239732-A1 | A METHOD FOR SYNTHESIZING XANTHOHUMOL | CYP46A1, CYP51A1, SQLE | ESR1 2025/4885AKR1B10 979/4885AKR1B1 1066/4885 |
| US-20250009620-A1 | Oral Care Compositions Comprising Hops Beta Acids | AP3S1, AP2S1, PROC | ESR1 4335/4885AKR1B10 3202/4885AKR1B1 3088/4885 |
| US-20230201295-A1 | Compositions and Methods for Managing or Improving Bone Disorders, Joint Disorders, Cartilage Disorders, or a Combination Thereof | MATR3, ACACA, COL2A1 | ESR1 4659/4885AKR1B10 1225/4885AKR1B1 1234/4885 |
| US-20230190852-A1 | COMPOSITIONS AND METHODS FOR JOINT HEALTH | PTGES, PTGES3, PTGES2 | ESR1 3736/4885AKR1B10 2429/4885AKR1B1 2475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.