Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 6/20 | 0.35 |
| ▸ | TOP2A | P11388 | 6/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048876 | 0.85 | SLC2A1 (0.36) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9048305 | 0.85 | LMNA (0.47) | POLBGSK3BTOP2ATOP2BKMT2A | |
| SCHEMBL9045251 | 0.85 | LMNA (0.47) | POLBGSK3BTOP2ATOP2BKMT2A | |
| SCHEMBL9045879 | 0.80 | ALDH1A1 (0.40) | POLBFOXO1GSK3BTOP2ATOP2B | |
| SCHEMBL9048884 | 0.77 | GSK3B (0.35) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9050270 | 0.74 | KDM4E (0.48) | TOP2BKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9047564 | 0.72 | ALDH1A1 (0.40) | KCNH2POLBHRH3GSK3BTOP2A | |
| SCHEMBL9044750 | 0.71 | ALDH1A1 (0.41) | POLBGSK3BTOP2ATOP2BKMT2A | |
| Hydrochloric Acid SCHEMBL9053691 | 0.70 | LMNA (0.41) | POLBGSK3BTOP2ATOP2BKMT2A | |
| Hydrochloric Acid SCHEMBL9053697 | 0.70 | LMNA (0.41) | POLBGSK3BTOP2ATOP2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700912-A1 | QUINOLONE DERIVATIVE OR SALT THEREOF, AND ANTIBACTERIAL CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1996-03-13 | — | — | EP | disclosed |