Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047377 | 0.88 | GABRA1 (0.36) | SMN1; SMN2MEN1KMT2ATAAR1KDM4E | |
| SCHEMBL198944 | 0.87 | GRM5 (0.35) | LTB4RLTB4R2GRM5 | |
| SCHEMBL27660692 | 0.83 | TAAR1 (0.39) | SMN1; SMN2MEN1KMT2ATAAR1KDM4E | |
| SCHEMBL9046269 | 0.82 | GABRA1 (0.38) | TAAR1LTB4RLTB4R2GRM5 | |
| SCHEMBL9046397 | 0.82 | TAAR1 (0.34) | TAAR1LTB4RLTB4R2GRM5 | |
| SCHEMBL6130256 | 0.81 | TAAR1 (0.42) | SMN1; SMN2MEN1KMT2ATAAR1KDM4E | |
| SCHEMBL27660867 | 0.80 | ALOX5 (0.41) | SMN1; SMN2MEN1KMT2ATAAR1PDE4A | |
| SCHEMBL9046566 | 0.80 | SMN1; SMN2 (0.33) | SMN1; SMN2MEN1KMT2ATAAR1KDM4E | |
| SCHEMBL8163553 | 0.80 | TAAR1 (0.39) | SMN1; SMN2MEN1KMT2ATAAR1KDM4E | |
| SCHEMBL9045688 | 0.79 | TAAR1 (0.37) | SMN1; SMN2MEN1KMT2ATAAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690854-A1 | 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1996-01-10 | — | — | EP | disclosed |