Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | HCN1 | O60741 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213271 | 0.92 | ALDH1A1 (0.57) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9043393 | 0.89 | ALDH1A1 (0.42) | ALDH1A1KMT2ASMN1; SMN2SIGMAR1ATM | |
| SCHEMBL9044507 | 0.87 | S1PR5 (0.46) | — | |
| SCHEMBL9045718 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9044419 | 0.82 | SMN1; SMN2 (0.48) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6765259 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KMT2ASMN1; SMN2SIGMAR1DRD1 | |
| SCHEMBL9044774 | 0.81 | KMT2A (0.44) | ALDH1A1KMT2ASIGMAR1THRBRECQL | |
| SCHEMBL9044861 | 0.80 | ALOX15 (0.41) | KMT2A | |
| SCHEMBL9045730 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KMT2ASMN1; SMN2SIGMAR1ATM | |
| SCHEMBL6762566 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KMT2ASIGMAR1DRD1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706527-A1 | SUBSTITUTED SPIROHETEROCYCLIC 1H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS | BAYER AG (DE) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001358-A1 | SUBSTITUTED SPIROHETEROCYCLIC 1H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-12 | — | — | WO | disclosed |