Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045960 | 0.93 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL9043393 | 0.90 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EKMT2ASIGMAR1 | |
| SCHEMBL9044419 | 0.83 | SMN1; SMN2 (0.48) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL6764643 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EKMT2ASIGMAR1 | |
| SCHEMBL9044742 | 0.82 | S1PR5 (0.46) | SIGMAR1 | |
| SCHEMBL9045718 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL9045472 | 0.81 | EPHX2 (0.44) | ALDH1A1MAPTKMT2ASIGMAR1CYP2D6 | |
| SCHEMBL9044569 | 0.81 | PYGL (0.35) | ALDH1A1KDM4EKMT2ACYP2D6MEN1 | |
| SCHEMBL6767232 | 0.81 | KMT2A (0.42) | ALDH1A1MAPTKDM4EKMT2ASIGMAR1 | |
| SCHEMBL6765253 | 0.78 | CTSS (0.42) | ALDH1A1MAPTKDM4EKMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706527-A1 | SUBSTITUTED SPIROHETEROCYCLIC 1H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS | BAYER AG (DE) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001358-A1 | SUBSTITUTED SPIROHETEROCYCLIC 1H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-12 | — | — | WO | disclosed |