Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047499 | 0.90 | SMN1; SMN2 (0.45) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL9827505 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL14341464 | 0.83 | ALOX5 (0.49) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL9047911 | 0.82 | L3MBTL1 (0.41) | SMN1; SMN2LMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL9046813 | 0.82 | HTR2A (0.41) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL9045048 | 0.82 | L3MBTL1 (0.45) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL198681 | 0.82 | CYP2A6 (0.38) | SMN1; SMN2CA1CA2CA7CA9 | |
| SCHEMBL4961769 | 0.81 | ALOX5 (0.42) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL9046757 | 0.81 | PTGS2 (0.44) | SMN1; SMN2ALOX5PTGS2MAPTKDM4E | |
| SCHEMBL9047165 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690854-A1 | 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1996-01-10 | — | — | EP | claimed |
| EP-0690854-A1 | 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1996-01-10 | — | — | EP | disclosed |