SCHEMBL9256209

SCHEMBL9256209

CC1C/C(=C/C2CCCCC2)C(=O)O1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 3/20 0.42
DYRK1B Q9Y463 3/20 0.42
CLK1 P49759 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.39
PIK3CA P42336 1/20 0.37
DYRK2 Q92630 1/20 0.37
EGFR P00533 1/20 0.35
MAOA P21397 3/20 0.33
MAOB P27338 2/20 0.33
MYC P01106 1/20 0.33
MAX P61244 1/20 0.33
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
CREBBP Q92793 1/20 0.32
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL664703 1.00 DYRK1A (0.42) DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA
SCHEMBL9256212 1.00 DYRK1A (0.42) DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA
SCHEMBL980374 0.72
SCHEMBL663387 0.72
SCHEMBL1904974 0.72
SCHEMBL19957009 0.72 DYRK1A (0.45) DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA
SCHEMBL22694016 0.71
SCHEMBL12675741 0.69 PPARG (0.45) DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA
SCHEMBL9709390 0.69 PPARG (0.45) DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA
SCHEMBL664822 0.69 PPARG (0.45) DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3543310-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-32 CHEMOURS CO FC LLC (US) 2024-07-03 EP disclosed
EP-3299435-B1 METHOD OF PREPARING A COMPOSITION COMPRISING HFC-1234YF CHEMOURS CO FC LLC (US) 2024-06-26 EP disclosed
US-20230265330-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2023-08-24 US disclosed
US-20230265330-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2023-08-24 US disclosed
US-11674067-B2 Compositions comprising a fluoroolefin THE CHEMOURS COMPANY FC, LLC (US) 2023-06-13 US disclosed
US-11674067-B2 Compositions comprising a fluoroolefin THE CHEMOURS COMPANY FC, LLC (US) 2023-06-13 US disclosed
US-20220389297-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2022-12-08 US disclosed
US-20210355360-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF THE CHEMOURS COMPANY FC, LLC (US) 2021-11-18 US disclosed
US-11124685-B2 Compositions comprising fluoroolefins and uses thereof THE CHEMOURS COMPANY FC, LLC (US) 2021-09-21 US disclosed
US-20210207014-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF THE CHEMOURS COMPANY FC, LLC (US) 2021-07-08 US disclosed
US-7208100-B2 1-ethoxy-1,1,2,2,3,3,4,4,4-nonafluorobutane refrigerant compositions comprising a fluoroether and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-24 US disclosed
US-7208100-B2 1-ethoxy-1,1,2,2,3,3,4,4,4-nonafluorobutane refrigerant compositions comprising a fluoroether and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-24 US disclosed
US-7201855-B2 1,1,1,3,3-pentafluorobutane refrigerant compositions comprising fluoroether and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-10 US disclosed
US-7201855-B2 1,1,1,3,3-pentafluorobutane refrigerant compositions comprising fluoroether and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-10 US disclosed
US-7198728-B2 1-ethoxy-1,1,2,2,3,3,4,4,4,-nonafluorobutane refrigerant compositions comprising a hydrocarbon and uses thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-03 US disclosed
US-7198728-B2 1-ethoxy-1,1,2,2,3,3,4,4,4,-nonafluorobutane refrigerant compositions comprising a hydrocarbon and uses thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-03 US disclosed
US-7157020-B2 Refrigerant compositions comprising performance enhancing additives E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-01-02 US disclosed
US-7157020-B2 Refrigerant compositions comprising performance enhancing additives E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-01-02 US disclosed
US-5416224-A Reaction of acetyldihydro-2-(3H)-furanone with aldehyde and alkali metal hydroxide HENKEL CORPORATION (US) 1995-05-16 US disclosed
WO-1992010487-A1 PROCESS FOR CONVERTING α-ACYL-SUBSTITUTED LACTONES TO α-ALKYLIDENE-SUBSTITUTED LACTONES HENKEL CORPORATION (US) 1992-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210355360-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF GFPT1, PFAS, TRMT1 DYRK1A 4075/4885DYRK1B 4150/4885CLK1 3524/4885
US-20210207014-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF GFPT1, PFAS, TRMT1 DYRK1A 4075/4885DYRK1B 4150/4885CLK1 3524/4885
US-11124685-B2 Compositions comprising fluoroolefins and uses thereof GFPT1, PFAS, TRMT1 DYRK1A 4075/4885DYRK1B 4150/4885CLK1 3524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.