Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046031 | 0.81 | FAAH (0.38) | FAAHMGAMGAASIMGAM2 | |
| SCHEMBL4640687 | 0.78 | FAAH (0.47) | ALDH1A1FAAHMGAMGAASI | |
| SCHEMBL10982819 | 0.78 | GAA (0.46) | ALDH1A1FAAHMGAMGAASI | |
| SCHEMBL7264663 | 0.77 | FAAH (0.37) | FAAHMGAMGAASIMGAM2 | |
| SCHEMBL9668517 | 0.76 | FAAH (0.38) | ALDH1A1FAAHMGAMGAASI | |
| SCHEMBL8970374 | 0.74 | FAAH (0.58) | ALDH1A1FAAH | |
| SCHEMBL14346946 | 0.73 | MGAM (0.41) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL11768048 | 0.73 | FAAH (0.46) | ALDH1A1FAAHGAA | |
| SCHEMBL10775601 | 0.73 | FAAH (0.66) | ALDH1A1FAAH | |
| SCHEMBL9048654 | 0.73 | MTNR1A (0.47) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115770-B2 | Thiazole Derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-06-19 | — | — | EP | disclosed |
| US-4695639-A | Thiazole derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-09-22 | — | — | US | disclosed |
| EP-0115770-B1 | THIAZOLE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1987-07-22 | — | — | EP | disclosed |
| EP-0115770-A1 | Thiazole Derivatives | Takeda Chemical Industries, Ltd. (JP) | 1984-08-15 | — | — | EP | disclosed |