⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046596 | 0.85 | MAOA (0.30) | — | |
| SCHEMBL9047815 | 0.84 | PREP (0.34) | — | |
| SCHEMBL9049370 | 0.83 | ACHE (0.31) | — | |
| SCHEMBL9050844 | 0.82 | ACHE (0.30) | — | |
| SCHEMBL9047602 | 0.81 | ACHE (0.30) | — | |
| SCHEMBL9050893 | 0.76 | PREP (0.38) | — | |
| SCHEMBL7301155 | 0.71 | PREP (0.35) | — | |
| SCHEMBL9048703 | 0.70 | PREP (0.41) | — | |
| SCHEMBL7295142 | 0.70 | PREP (0.34) | — | |
| SCHEMBL9048506 | 0.70 | CHRM2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536399-B1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5407950-A | Brain disorders, senile dementia | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0536399-A1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-14 | — | — | EP | disclosed |