Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.63 |
| ▸ | HPGD | P15428 | 6/20 | 0.63 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046458 | 0.91 | LMNA (0.66) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9046436 | 0.90 | ALDH1A1 (0.78) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9043027 | 0.90 | LMNA (0.80) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9434537 | 0.90 | LMNA (0.62) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| Hydrochloric Acid SCHEMBL9433655 | 0.89 | ALDH1A1 (0.80) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL16518632 | 0.88 | LMNA (0.81) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9047446 | 0.86 | LMNA (0.63) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9043943 | 0.85 | LMNA (0.62) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9433406 | 0.85 | LMNA (0.62) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9433221 | 0.83 | LMNA (0.59) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422485-B1 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1996-04-03 | — | — | EP | disclosed |