Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | HPGD | P15428 | 7/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046336 | 0.90 | LMNA (0.47) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9433406 | 0.88 | LMNA (0.62) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9043027 | 0.85 | LMNA (0.80) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9046458 | 0.84 | LMNA (0.66) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9045932 | 0.83 | ALDH1A1 (0.65) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9046329 | 0.82 | LMNA (0.59) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9047446 | 0.82 | LMNA (0.63) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9046436 | 0.81 | ALDH1A1 (0.78) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9434537 | 0.81 | LMNA (0.62) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10884454 | 0.81 | KDM4E (0.70) | LMNAALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300643-A | Viricides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| US-5217972-A | QUINOLONECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIVIRAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-08 | — | — | US | disclosed |