Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.40 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 2/20 | 0.36 |
| ▸ | DNA2 | P51530 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140106 | 0.82 | KDM4E (0.53) | KDM4ETET2TET1CSNK2A2CSNK2B | |
| Hydrochloric Acid SCHEMBL9047371 | 0.81 | TOP2A (0.42) | KDM4ECYP1A2HSD17B10TOP2ATOP2B | |
| SCHEMBL9047376 | 0.81 | KDM4E (0.45) | KDM4EHSD17B10TOP2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9044858 | 0.81 | KDM4E (0.44) | KDM4EHSD17B10TOP2AALDH1A1HPGD | |
| SCHEMBL9047491 | 0.79 | ALDH1A1 (0.47) | TOP2ATOP2BALDH1A1KMT2A | |
| SCHEMBL9045281 | 0.79 | ALDH1A1 (0.47) | TOP2ATOP2BALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL9049612 | 0.78 | ALDH1A1 (0.46) | TOP2ATOP2BALDH1A1KMT2A | |
| SCHEMBL1878010 | 0.76 | KDM4E (0.51) | KDM4ETET2TET1CSNK2A2CSNK2B | |
| SCHEMBL10962735 | 0.74 | TOP2A (0.47) | KDM4ETET2TET1CSNK2A2CSNK2B | |
| SCHEMBL30307775 | 0.73 | KDM4E (0.49) | KDM4ETET2TET1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713487-A1 | NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES | DONG WHA PHARMACEUTICAL INDUSTRIAL CO. LTD. (KR) | 1996-05-29 | — | — | EP | disclosed |