Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9044858 | 0.99 | KDM4E (0.44) | KDM4EADRA2BMAPK1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9047371 | 0.89 | TOP2A (0.42) | KDM4EHPGDHSD17B10ALDH1A1TOP1 | |
| SCHEMBL9047491 | 0.84 | ALDH1A1 (0.47) | ALDH1A1POLBTOP1TOP2AKMT2A | |
| SCHEMBL9045281 | 0.84 | ALDH1A1 (0.47) | ALDH1A1POLBTOP1TOP2AKMT2A | |
| Hydrochloric Acid SCHEMBL9049612 | 0.84 | ALDH1A1 (0.46) | ALDH1A1POLBTOP1TOP2AKMT2A | |
| SCHEMBL9044591 | 0.83 | KDM4E (0.46) | KDM4EADRA2BMAPK1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9057379 | 0.82 | KDM4E (0.45) | KDM4EADRA2BMAPK1HPGDHSD17B10 | |
| SCHEMBL9045950 | 0.81 | KDM4E (0.41) | KDM4EHPGDHSD17B10ALDH1A1TOP2A | |
| SCHEMBL11202634 | 0.78 | KDM4E (0.52) | KDM4EADRA2BMAPK1HPGDHSD17B10 | |
| SCHEMBL10862553 | 0.77 | KDM4E (0.51) | KDM4EADRA2BMAPK1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713487-A1 | NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES | DONG WHA PHARMACEUTICAL INDUSTRIAL CO. LTD. (KR) | 1996-05-29 | — | — | EP | disclosed |