Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.72 |
| ▸ | TSHR | P16473 | 3/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.72 |
| ▸ | HTR2B | P41595 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21563477 | 0.93 | ALDH1A1 (0.62) | ALDH1A1HSD17B10ALOX12L3MBTL1TSHR | |
| SCHEMBL395770 | 0.88 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ALOX12L3MBTL1TSHR | |
| SCHEMBL15138258 | 0.87 | HSD17B10 (0.55) | ALDH1A1HSD17B10ALOX12L3MBTL1TSHR | |
| SCHEMBL7896372 | 0.85 | ALDH1A1 (1.00) | ALDH1A1HSD17B10ALOX12L3MBTL1TSHR | |
| SCHEMBL13663470 | 0.85 | ALDH1A1 (1.00) | ALDH1A1HSD17B10ALOX12L3MBTL1TSHR | |
| N,N'-Diphenyl-P-Phenylenediamine SCHEMBL42930 | 0.85 | ALDH1A1 (1.00) | ALDH1A1HSD17B10ALOX12L3MBTL1TSHR | |
| SCHEMBL9480038 | 0.85 | ALDH1A1 (1.00) | ALDH1A1HSD17B10ALOX12L3MBTL1TSHR | |
| SCHEMBL5116724 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HSD17B10ALOX12L3MBTL1TSHR | |
| N,N'-Diphenyl-P-Phenylenediamine SCHEMBL8465009 | 0.82 | ALDH1A1 (0.93) | ALDH1A1HSD17B10ALOX12L3MBTL1TSHR | |
| N,N'-Diphenyl-P-Phenylenediamine SCHEMBL30067131 | 0.82 | ALDH1A1 (0.93) | ALDH1A1HSD17B10ALOX12L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160031863-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | BIOFOCUS DPI LIMITED (GB) | 2016-02-04 | — | — | US | claimed |
| CN-103204797-B | The arylamine class luminous organic material of dihydro pentacene and preparation method | Jilin Optical and Electronic Materials Co., Ltd. (CN) | 2016-01-20 | — | — | CN | claimed |
| US-20150166604-A1 | Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof | TREVENA, INC. | 2015-06-18 | — | — | US | claimed |
| US-20140357562-A1 | Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof | TREVENA, INC. | 2014-12-04 | — | — | US | claimed |
| US-8853207-B2 | Heterocyclic pyrazole compounds, method for preparing the same and use thereof | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2014-10-07 | — | — | US | claimed |
| WO-2014159214-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI FOUNDATION, INC. (US) | 2014-10-02 | — | — | WO | claimed |
| US-20130274176-A1 | BETA-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF | TREVENA, INC. (US) | 2013-10-17 | — | — | US | claimed |
| US-20130274255-A1 | HETEROCYCLIC PYRAZOLE COMPOUNDS, METHOD FOR PREPARING THE SAME AND USE THEREOF | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2013-10-17 | — | — | US | claimed |
| EP-2376101-A2 | ß-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF | Trevena, Inc. (US) | 2011-10-19 | — | — | EP | claimed |
| US-20100184701-A1 | Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof | TREVENA, INC. | 2010-07-22 | — | — | US | claimed |
| WO-2010077339-A2 | β-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF | TREVENA, INC. (US) | 2010-07-08 | — | — | WO | claimed |
| US-6355616-B1 | FUNGICIDE OLIGOPEOTIDES | XOMA (US) TECHNOLOGY LTD. | 2002-03-12 | — | — | US | claimed |
| CN-1102643-A | Substituted derivatives of diaminophthalimide | CIBA GEIGY AG (CH) | 1995-05-17 | — | — | CN | claimed |
| US-RE50267-E1 | Modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2025-01-14 | — | — | US | disclosed |
| US-20250009693-A1 | MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2025-01-09 | — | — | US | disclosed |
| US-12128026-B2 | Selective androgen receptor degrader (SARD) ligands and methods of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2024-10-29 | — | — | US | disclosed |
| CN-86105891-A | Desinsection ether | — | 1987-02-25 | — | — | CN | disclosed |
| US-4411904-A | Diphenylpropanamines, compositions thereof and use thereof | WARNER-LAMBERT COMPANY (US) | 1983-10-25 | — | — | US | disclosed |
| US-4364954-A | NEUROLEPTIC AGENT | WARNER-LAMBERT COMPANY (US) | 1982-12-21 | — | — | US | disclosed |
| US-4292321-A | 1,3,8-Triazaspirodecane-4-ones, pharmaceutical compositions thereof and method of use thereof | WARNER-LAMBERT COMPANY (US) | 1981-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166604-A1 | Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof | ARRB1, ADRB1, ADRB3 | ALDH1A1 3985/4885HSD17B10 2466/4885ALOX12 3984/4885 |
| US-20130274176-A1 | BETA-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF | ARRB1, ADRB1, ADRB3 | ALDH1A1 3985/4885HSD17B10 2466/4885ALOX12 3984/4885 |
| US-12128026-B2 | Selective androgen receptor degrader (SARD) ligands and methods of use thereof | AR, AHR, BRDT | ALDH1A1 1784/4885HSD17B10 1168/4885ALOX12 778/4885 |
| US-20130274255-A1 | HETEROCYCLIC PYRAZOLE COMPOUNDS, METHOD FOR PREPARING THE SAME AND USE THEREOF | RET, FLT3, FGFR1 | ALDH1A1 1491/4885HSD17B10 2657/4885ALOX12 4587/4885 |
| US-20250009693-A1 | MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | PTGIR, PTGIS, TBXA2R | ALDH1A1 2589/4885HSD17B10 1408/4885ALOX12 72/4885 |
| US-20140357562-A1 | Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof | ARRB1, ADRB1, ADRB3 | ALDH1A1 3985/4885HSD17B10 2466/4885ALOX12 3984/4885 |
| US-20100184701-A1 | Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof | ARRB1, ADRB1, ADRB3 | ALDH1A1 3985/4885HSD17B10 2466/4885ALOX12 3984/4885 |
| US-20160031863-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | HDAC1, HDAC7, HDAC5 | ALDH1A1 559/4885HSD17B10 177/4885ALOX12 3245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.