Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18243554 | 0.87 | ALDH1A1 (0.33) | ALDH1A1TAAR1 | |
| SCHEMBL198681 | 0.85 | CYP2A6 (0.38) | ALDH1A1CYP1A2CYP2A6CA1CA2 | |
| SCHEMBL533943 | 0.80 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP2A6MAOAMAOB | |
| SCHEMBL9045061 | 0.79 | GABRA1 (0.45) | ALDH1A1CYP1A2TAAR1 | |
| SCHEMBL10830808 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2A6MAOAMAOB | |
| SCHEMBL533804 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2A6CA1CA2 | |
| SCHEMBL1610192 | 0.79 | CYP2A6 (0.36) | ALDH1A1CYP1A2CYP2A6CA1CA2 | |
| SCHEMBL9047151 | 0.78 | EED (0.36) | ALDH1A1TAAR1 | |
| SCHEMBL9049748 | 0.78 | TAAR1 (0.41) | ALDH1A1CYP1A2CYP2A6MAOATAAR1 | |
| SCHEMBL9046091 | 0.78 | GABRA1 (0.44) | CYP1A2CA1CA2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690854-A1 | 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1996-01-10 | — | — | EP | disclosed |