Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | TOP2A | P11388 | 3/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | BAX | Q07812 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9045062 | 0.99 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL9043926 | 0.88 | HPGD (0.48) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL9047805 | 0.88 | ALDH1A1 (0.72) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL9433661 | 0.87 | ALDH1A1 (0.74) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL9045941 | 0.84 | LMNA (0.45) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL9044502 | 0.84 | LMNA (0.40) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL9044293 | 0.83 | ALDH1A1 (0.66) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL2858133 | 0.81 | KDM4E (0.77) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL10915571 | 0.81 | KDM4E (0.62) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL1857925 | 0.80 | KDM4E (0.76) | ALDH1A1KDM4ELMNAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422485-B1 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1996-04-03 | — | — | EP | disclosed |
| EP-0422485-A2 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |