Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 3/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047003 | 1.00 | L3MBTL1 (0.41) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9841831 | 0.88 | L3MBTL1 (0.44) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9341462 | 0.88 | L3MBTL1 (0.44) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9342381 | 0.86 | P2RY12 (0.35) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9044292 | 0.80 | L3MBTL1 (0.41) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9044038 | 0.78 | L3MBTL1 (0.39) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9045922 | 0.78 | TAS1R3 (0.35) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9340151 | 0.76 | L3MBTL1 (0.42) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9483012 | 0.76 | L3MBTL1 (0.40) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9340437 | 0.76 | L3MBTL1 (0.40) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432677-B1 | N-(pyrrolo[2,3-d]pyrimidin-3-ylacyl)-glutamic acid derivatives | UNIV PRINCETON (US) | 1996-03-06 | — | — | EP | disclosed |
| US-5344932-A | N-(pyrrolo(2,3-d)pyrimidin-3-ylacyl)-glutamic acid derivatives | TRUSTEES OF PRINCETON UNIVERSITY (US) | 1994-09-06 | — | — | US | disclosed |
| US-5248775-A | Pyrrolo(2,3-d)pyrimidines | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1993-09-28 | — | — | US | disclosed |
| EP-0432677-A1 | N-(pyrrolo[2,3-d]pyrimidin-3-ylacyl)-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1991-06-19 | — | — | EP | disclosed |