Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MYC | P01106 | 2/20 | 0.39 |
| ▸ | WDR5 | P61964 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | SLC34A2 | O95436 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 2/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045788 | 0.73 | MEN1 (0.47) | ALDH1A1KMT2AKDM4ECDK2 | |
| SCHEMBL9098198 | 0.72 | MYC (0.59) | ALDH1A1RECQLMYCWDR5EPHX2 | |
| SCHEMBL211069 | 0.71 | EHMT2 (0.44) | ALDH1A1RAB9AMYCWDR5KMT2A | |
| SCHEMBL25325181 | 0.70 | RAB9A (0.51) | ALDH1A1RECQLRAB9AKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL9047937 | 0.70 | L3MBTL1 (0.45) | ALDH1A1RAB9AMYCWDR5KMT2A | |
| SCHEMBL2907382 | 0.69 | GCK (0.41) | MYCWDR5CDK2 | |
| SCHEMBL6249003 | 0.68 | KDM4E (0.49) | ALDH1A1RECQLRAB9AKMT2AKDM4E | |
| SCHEMBL28737917 | 0.68 | RAB9A (0.49) | ALDH1A1RECQLRAB9AKMT2AKDM4E | |
| SCHEMBL3323097 | 0.68 | RAB9A (0.49) | ALDH1A1RECQLRAB9AKMT2AKDM4E | |
| Methane SCHEMBL3555245 | 0.67 | KMT2A (0.50) | ALDH1A1RECQLKMT2AEPHX2SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412404-B1 | Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5369107-A | Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-29 | — | — | US | disclosed |
| US-5256675-A | Antirheumatic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| EP-0412404-A2 | Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-13 | — | — | EP | disclosed |