SCHEMBL9047207

SCHEMBL9047207

NC(=O)C(C1CCc2c(cccc2OCC(=O)O)C1)N(c1ccccc1)c1cccnc1

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.52
PTGIR P43119 18/20 0.49
PTGDR Q13258 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9050333 0.92 PTGIR (0.56) TBXAS1PTGIRPTGDR
SCHEMBL9427288 0.88 TBXAS1 (0.40) TBXAS1PTGIRPTGDR
SCHEMBL9047215 0.83 TBXAS1 (0.57) TBXAS1PTGIRPTGDR
SCHEMBL9048217 0.82 TRPM8 (0.34) TBXAS1PTGIR
SCHEMBL9427367 0.79 PTGIR (0.56) PTGIRPTGDR
SCHEMBL9427442 0.79 PTGIR (0.41) PTGIR
SCHEMBL9051601 0.78 TRPM8 (0.32) PTGIR
SCHEMBL9048137 0.76 PTGIR (0.64) TBXAS1PTGIRPTGDR
SCHEMBL9427242 0.76 PTGIR (0.59) TBXAS1PTGIRPTGDR
SCHEMBL9048122 0.75 PTGIR (0.58) TBXAS1PTGIRPTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542203-B1 Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists ONO PHARMACEUTICAL CO (JP) 1996-07-03 EP claimed
US-5344836-A Fused benzeneoxyacetic acid derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1994-09-06 US claimed
EP-0542203-A2 Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists ONO PHARMACEUTICAL CO., LTD. (JP) 1993-05-19 EP claimed