Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PTGIR | P43119 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568065 | 0.82 | KCNA5 (0.30) | — | |
| SCHEMBL9048217 | 0.79 | TRPM8 (0.34) | TRPM8NR1I2TAOK1TSHRPTGIR | |
| SCHEMBL9047207 | 0.78 | TBXAS1 (0.52) | PTGIR | |
| SCHEMBL9427288 | 0.77 | TBXAS1 (0.40) | TRPM8NR1I2PTGIR | |
| SCHEMBL9567954 | 0.72 | MTNR1A (0.34) | TRPM8 | |
| SCHEMBL9568061 | 0.71 | PTGIR (0.36) | PTGIRSLC18A3 | |
| SCHEMBL9427435 | 0.68 | PTGIR (0.33) | TRPM8PTGIR | |
| SCHEMBL9050333 | 0.67 | PTGIR (0.56) | PTGIR | |
| SCHEMBL9568045 | 0.67 | TAOK1 (0.39) | TRPM8NR1I2TAOK1SLC18A3 | |
| SCHEMBL9427442 | 0.65 | PTGIR (0.41) | PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |