SCHEMBL9047232

SCHEMBL9047232

C1=CCC2=c3nc(Cc4ccncc4)sc3=CC2=C1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9046094 0.86 ADORA2A (0.33)
SCHEMBL9095038 0.76
SCHEMBL4452676 0.75
SCHEMBL9097631 0.75 CYP2C9 (0.32)
SCHEMBL9048189 0.73
SCHEMBL9098582 0.73 TBXAS1 (0.34)
SCHEMBL9047973 0.71 MEN1 (0.32) RAB9A
SCHEMBL4960018 0.71
SCHEMBL9047832 0.71 HRH3 (0.33)
SCHEMBL9047746 0.71 L3MBTL1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0749966-A1 5-HT 3 RECEPTOR AGONIST, NOVEL THIAZOLE DERIVATIVE, AND INTERMEDIATE THEREFOR YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1996-12-27 EP disclosed