Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252771 | 0.90 | ALOX5 (0.41) | KCNA3ALOX5 | |
| SCHEMBL13444795 | 0.74 | ALOX5 (0.54) | ALOX5 | |
| SCHEMBL9086686 | 0.73 | KCNA3 (0.40) | KCNA3ALOX5 | |
| SCHEMBL1121005 | 0.71 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL8698139 | 0.71 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9581200 | 0.71 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL8186215 | 0.71 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL9253227 | 0.70 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL19615116 | 0.69 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL9229297 | 0.68 | ALOX5 (0.45) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555068-B1 | Oxime derivatives as 5-lipoxygenase inhibitors | ZENECA LTD (GB) | 1996-04-10 | — | — | EP | disclosed |
| US-5484805-A | LIPOXYGENASE INHIBITORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1996-01-16 | — | — | US | disclosed |
| US-5482966-A | LIPOXYGENASE ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS | ZENECA LIMITED (GB) | 1996-01-09 | — | — | US | disclosed |
| EP-0462812-B1 | Pyran derivatives as inhibitors of 5-lipoxygenase | ZENECA LTD (GB) | 1995-12-06 | — | — | EP | disclosed |
| US-5359063-A | Lipoxygenase inhibitor | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-10-25 | — | — | US | disclosed |
| US-5332757-A | Enzyme inhibitors | ZENECA LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |
| EP-0555068-A1 | Oxime derivatives as 5-lipoxygenase inhibitors | ZENECA LIMITED (GB) | 1993-08-11 | — | — | EP | disclosed |
| US-5217978-A | Lipoxygenase inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-08 | — | — | US | disclosed |
| EP-0462812-A2 | Pyran derivatives as inhibitors of 5-lipoxygenase | ZENECA LIMITED (GB) | 1991-12-27 | — | — | EP | disclosed |