Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 11/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047613 | 0.90 | KCNA3 (0.43) | ALOX5KCNA3 | |
| SCHEMBL31353592 | 0.73 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9255138 | 0.72 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL24377797 | 0.69 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL9259587 | 0.69 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL29239381 | 0.68 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL31353191 | 0.67 | LPL (0.41) | ALOX5 | |
| SCHEMBL31353301 | 0.67 | LPL (0.41) | ALOX5 | |
| SCHEMBL31353180 | 0.67 | LPL (0.41) | ALOX5 | |
| SCHEMBL26876154 | 0.67 | ALOX5 (0.46) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432194-A | Antiallergens, antinflammatory agents | ABBOTT LABORATORIES (US) | 1995-07-11 | — | — | US | disclosed |
| WO-1994026264-A1 | (4-ALKOXYPYRAN-4-YL) SUBSTITUTED ARYLALKYLARYL-, ARYLALKENYLARYL-, AND ARYLALKYNYLARYLUREA INHIBITORS OF 5-LIPOXYGENASE | ABBOTT LABORATORIES (US) | 1994-11-24 | — | — | WO | disclosed |
| US-5346914-A | Antiallergens, antiinflammatory agents | ABBOTT LABORATORIES (US) | 1994-09-13 | — | — | US | disclosed |