Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255138 | 0.91 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL7481034 | 0.76 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL9100023 | 0.72 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL9047613 | 0.70 | KCNA3 (0.43) | ALOX5 | |
| SCHEMBL1598547 | 0.70 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9027778 | 0.70 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL9085434 | 0.69 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9229297 | 0.69 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL8630364 | 0.69 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9048284 | 0.69 | ALOX5 (0.41) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432194-A | Antiallergens, antinflammatory agents | ABBOTT LABORATORIES (US) | 1995-07-11 | — | — | US | disclosed |
| WO-1994026264-A1 | (4-ALKOXYPYRAN-4-YL) SUBSTITUTED ARYLALKYLARYL-, ARYLALKENYLARYL-, AND ARYLALKYNYLARYLUREA INHIBITORS OF 5-LIPOXYGENASE | ABBOTT LABORATORIES (US) | 1994-11-24 | — | — | WO | disclosed |