Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046917 | 0.90 | DPP4 (0.48) | DPP4CHRM2DRD1EPHA2FLT4 | |
| SCHEMBL8083243 | 0.89 | DPP4 (0.65) | DPP4CHRM2DRD1EPHA2FLT4 | |
| SCHEMBL9046856 | 0.88 | DPP4 (0.46) | DPP4CHRM2DRD1EPHA2FLT4 | |
| SCHEMBL9046530 | 0.83 | KDM4E (0.46) | LMNAKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL9045603 | 0.83 | ALDH1A1 (0.42) | DPP4CHRM2LMNAKDM4EHSD17B10 | |
| SCHEMBL7850682 | 0.82 | DPP4 (0.51) | DPP4CHRM2DRD1EPHA2FLT4 | |
| SCHEMBL9692906 | 0.82 | DPP4 (0.47) | DPP4CHRM2DRD1EPHA2FLT4 | |
| SCHEMBL9046626 | 0.81 | ALDH1A1 (0.53) | DPP4CHRM2LMNAKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL9692856 | 0.81 | DPP4 (0.47) | DPP4CHRM2DRD1EPHA2FLT4 | |
| SCHEMBL9645658 | 0.81 | KMT2A (0.56) | DPP4CHRM2DRD1EPHA2FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588166-B1 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1996-06-05 | — | — | EP | disclosed |
| EP-0588166-A2 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-03-23 | — | — | EP | disclosed |