Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | STAT3 | P40763 | 3/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | RAC1 | P63000 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043171 | 0.91 | TOP1 (0.42) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9047795 | 0.87 | ALDH1A1 (0.60) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL10911343 | 0.86 | ALDH1A1 (0.54) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9045182 | 0.85 | NPC1 (0.40) | ALDH1A1KDM4EPOLBPIM1TOP1 | |
| SCHEMBL10915726 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL10912940 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL6213803 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL6214790 | 0.82 | KDM4E (0.49) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL10913630 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL10915500 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422485-B1 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1996-04-03 | — | — | EP | disclosed |