Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | PIM1 | P11309 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | TOP1 | P11387 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043165 | 0.91 | TOP1 (0.55) | ALDH1A1POLBKDM4EHSP90AA1RXFP1 | |
| SCHEMBL9047798 | 0.87 | ALDH1A1 (0.46) | ALDH1A1POLBKDM4EHSP90AA1RXFP1 | |
| SCHEMBL9869480 | 0.85 | ALDH1A1 (0.72) | ALDH1A1POLBKDM4EHSP90AA1RXFP1 | |
| SCHEMBL9045179 | 0.84 | LMNA (0.48) | ALDH1A1POLBKDM4EHSP90AA1RXFP1 | |
| SCHEMBL7009332 | 0.83 | TOP1 (0.58) | ALDH1A1POLBKDM4EHSP90AA1RXFP1 | |
| SCHEMBL9869850 | 0.82 | ALDH1A1 (0.65) | ALDH1A1POLBKDM4EHSP90AA1RXFP1 | |
| SCHEMBL9869597 | 0.82 | ALDH1A1 (0.64) | ALDH1A1POLBKDM4EHSP90AA1RXFP1 | |
| SCHEMBL6213800 | 0.81 | ALDH1A1 (0.67) | ALDH1A1POLBKDM4EHSP90AA1RXFP1 | |
| SCHEMBL10372132 | 0.80 | ALDH1A1 (0.65) | ALDH1A1POLBKDM4EHSP90AA1RXFP1 | |
| SCHEMBL6214789 | 0.80 | KDM4E (0.65) | ALDH1A1POLBKDM4EHSP90AA1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422485-B1 | Quinolone carboxylic acid derivatives, process for their preparation and their use | BAYER AG (DE) | 1996-04-03 | — | — | EP | disclosed |
| US-5300643-A | Viricides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| US-5217972-A | QUINOLONECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIVIRAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-08 | — | — | US | disclosed |