Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 14/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050669 | 0.82 | MAOA (0.49) | GRM2MAOAMAOBSLC9A1 | |
| SCHEMBL9048647 | 0.82 | NLRP3 (0.38) | GRM2MAOAMAOB | |
| SCHEMBL9049457 | 0.78 | MAOA (0.46) | MAOAMAOB | |
| SCHEMBL8802069 | 0.73 | GRM2 (0.36) | GRM2MAOAMAOBCA2 | |
| SCHEMBL3331808 | 0.72 | GRM2 (0.65) | GRM2 | |
| SCHEMBL6955426 | 0.72 | GRM2 (0.65) | GRM2 | |
| SCHEMBL8799676 | 0.72 | GRM2 (0.65) | GRM2 | |
| SCHEMBL5235135 | 0.72 | GRM2 (0.40) | GRM2MAOAMAOB | |
| SCHEMBL18770241 | 0.72 | MAOB (0.48) | GRM2MAOAMAOB | |
| SCHEMBL12964562 | 0.72 | MAOB (0.48) | GRM2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693491-A1 | Oxazolidinones substituted by 5-membered heteroaryl group as antibacterial medicine | BAYER AG (DE) | 1996-01-24 | — | — | EP | disclosed |