Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CALML3 | P27482 | 6/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049457 | 0.84 | MAOA (0.46) | MAOAMAOBCALML3F10 | |
| SCHEMBL9047854 | 0.82 | GRM2 (0.38) | MAOAMAOBSLC9A1GRM2 | |
| SCHEMBL9048647 | 0.82 | NLRP3 (0.38) | MAOAMAOBGRM2 | |
| SCHEMBL9047627 | 0.78 | MAOA (0.44) | MAOAMAOBCALML3GRM2F10 | |
| SCHEMBL8867980 | 0.71 | MAOB (0.52) | MAOAMAOBCALML3GRM2F10 | |
| SCHEMBL9077363 | 0.69 | SLC9A1 (0.36) | SLC9A1 | |
| SCHEMBL851157 | 0.68 | MAOA (0.66) | MAOAMAOBCALML3GRM2 | |
| SCHEMBL851156 | 0.68 | MAOA (0.66) | MAOAMAOBCALML3GRM2 | |
| SCHEMBL8801477 | 0.67 | MAOA (0.49) | MAOAMAOBCALML3GRM2 | |
| SCHEMBL412168 | 0.67 | MAOA (0.58) | MAOAMAOBCALML3GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8053443-A | — | — | None | — | — | JP | disclosed |
| JP-H0853443-A | 5-MEMBERED HETEROARYL-OXAZOLIDINONES | BAYER AG | 1996-02-27 | — | — | JP | disclosed |
| EP-0693491-A1 | Oxazolidinones substituted by 5-membered heteroaryl group as antibacterial medicine | BAYER AG (DE) | 1996-01-24 | — | — | EP | disclosed |