Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048832 | 0.80 | KCNH2 (0.40) | HTR3A | |
| SCHEMBL9046975 | 0.77 | AKR1C3 (0.44) | KMT2ALMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL25428769 | 0.69 | LMNA (0.50) | KMT2ALMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15533464 | 0.69 | KMT2A (0.46) | KMT2ALMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL10836168 | 0.68 | NOTUM (0.56) | KMT2ALMNAL3MBTL1OXER1MAPK1 | |
| SCHEMBL3361461 | 0.67 | ALDH1A1 (0.63) | KMT2ALMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL14228924 | 0.67 | OXER1 (0.61) | LMNASMN1; SMN2L3MBTL1OXER1CREBBP | |
| SCHEMBL14745414 | 0.67 | LMNA (0.71) | KMT2ALMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL1578054 | 0.67 | ALDH1A1 (0.59) | LMNAALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL20838595 | 0.66 | KMT2A (0.58) | KMT2AALDH1A1SMN1; SMN2L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714896-A1 | INDOL DERIVATIVES USEFUL FOR THE TREATMENT OF MIGRAINE, COMPOSITION AND UTILIZATION | VITA-INVEST, S.A. (ES) | 1996-06-05 | — | — | EP | disclosed |