Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20096201 | 0.88 | KDM2B (0.38) | KDM2BMEN1KMT2AL3MBTL3HRH3 | |
| SCHEMBL20096200 | 0.88 | KDM2B (0.38) | KDM2BMEN1KMT2AL3MBTL3HRH3 | |
| SCHEMBL20095966 | 0.86 | KDM2B (0.42) | KDM2BL3MBTL3HRH3 | |
| SCHEMBL20096182 | 0.86 | KDM2B (0.42) | KDM2BL3MBTL3HRH3 | |
| SCHEMBL20095968 | 0.86 | KDM2B (0.42) | KDM2BL3MBTL3HRH3 | |
| SCHEMBL153765 | 0.83 | L3MBTL3 (0.39) | KDM2BL3MBTL3HTR6PDCD1CD274 | |
| SCHEMBL150219 | 0.81 | CYP2D6 (0.39) | L3MBTL3PDCD1CD274CYP2D6HRH3 | |
| SCHEMBL155515 | 0.81 | CYP2D6 (0.39) | L3MBTL3PDCD1CD274CYP2D6HRH3 | |
| SCHEMBL27855229 | 0.79 | L3MBTL3 (0.36) | KDM2BL3MBTL3PDCD1CD274CYP2D6 | |
| SCHEMBL6636518 | 0.78 | KDM2B (0.39) | KDM2BL3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61085387-A | — | — | None | — | — | JP | disclosed |
| EP-0749966-A1 | 5-HT 3 RECEPTOR AGONIST, NOVEL THIAZOLE DERIVATIVE, AND INTERMEDIATE THEREFOR | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |
| JP-S6185387-A | 3-BENZOYLQUINOLIZIDINE DERIVATIVE | HOKURIKU SEIYAKU CO LTD | 1986-04-30 | — | — | JP | disclosed |