Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 9/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20096200 | 1.00 | KDM2B (0.38) | KDM2BL3MBTL3HRH3MEN1KMT2A | |
| SCHEMBL20095966 | 0.90 | KDM2B (0.42) | KDM2BL3MBTL3HRH3DPP4 | |
| SCHEMBL20096182 | 0.90 | KDM2B (0.42) | KDM2BL3MBTL3HRH3DPP4 | |
| SCHEMBL20095968 | 0.90 | KDM2B (0.42) | KDM2BL3MBTL3HRH3DPP4 | |
| SCHEMBL9048012 | 0.88 | KDM2B (0.41) | KDM2BL3MBTL3HRH3MEN1KMT2A | |
| SCHEMBL17284681 | 0.83 | L3MBTL3 (0.34) | KDM2BL3MBTL3 | |
| SCHEMBL18023770 | 0.83 | ALDH1A1 (0.50) | KDM2BL3MBTL3MEN1KMT2A | |
| SCHEMBL20376510 | 0.83 | ALDH1A1 (0.50) | KDM2BL3MBTL3MEN1KMT2A | |
| SCHEMBL6636518 | 0.82 | KDM2B (0.39) | KDM2BL3MBTL3 | |
| SCHEMBL9045610 | 0.82 | KDM2B (0.39) | KDM2BL3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018072602-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2018-04-26 | — | — | WO | disclosed |