Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050611 | 0.93 | KMT2A (0.44) | KMT2AL3MBTL1MEN1ALDH1A1GAA | |
| SCHEMBL9048971 | 0.84 | PTGIR (0.37) | ALDH1A1LMNASLC6A4SLC6A3KDM4E | |
| SCHEMBL9048207 | 0.83 | PTGIR (0.46) | KMT2AL3MBTL1MEN1ALDH1A1GAA | |
| SCHEMBL9048344 | 0.81 | PTGIR (0.45) | KMT2AL3MBTL1MEN1ALDH1A1GAA | |
| SCHEMBL9048134 | 0.80 | PTGIR (0.45) | KMT2AL3MBTL1MEN1ALDH1A1GAA | |
| SCHEMBL9567998 | 0.79 | PRMT5 (0.49) | KMT2AL3MBTL1MEN1ALDH1A1GAA | |
| SCHEMBL9051611 | 0.79 | PTGIR (0.54) | — | |
| SCHEMBL9051610 | 0.79 | SLC6A4 (0.40) | KMT2AL3MBTL1MEN1ALDH1A1GAA | |
| SCHEMBL9047720 | 0.78 | PTGIR (0.43) | — | |
| SCHEMBL9049008 | 0.76 | LMNA (0.48) | KMT2AL3MBTL1MEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |