Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490708 | 0.78 | MAOA (0.40) | SIGMAR1ACHEBCHEMEN1USP2 | |
| SCHEMBL4725456 | 0.75 | SIGMAR1 (0.46) | SIGMAR1ACHEBCHEMEN1USP2 | |
| SCHEMBL7732342 | 0.75 | SIGMAR1 (0.42) | SIGMAR1ACHEBCHEMEN1USP2 | |
| SCHEMBL4573279 | 0.75 | SIGMAR1 (0.42) | SIGMAR1ACHEBCHEMEN1USP2 | |
| SCHEMBL4725450 | 0.75 | SIGMAR1 (0.42) | SIGMAR1ACHEBCHEMEN1USP2 | |
| SCHEMBL11347558 | 0.72 | SIGMAR1 (0.43) | SIGMAR1ACHEBCHEMEN1USP2 | |
| SCHEMBL13751428 | 0.71 | HTR3A (0.35) | LMNASMN1; SMN2MAOAMAOB | |
| SCHEMBL6801284 | 0.69 | SIGMAR1 (0.44) | SIGMAR1ACHEBCHEMEN1USP2 | |
| SCHEMBL14608794 | 0.68 | SIGMAR1 (0.43) | SIGMAR1ACHEBCHEMEN1USP2 | |
| SCHEMBL18895799 | 0.68 | SIGMAR1 (0.61) | SIGMAR1ACHEBCHEMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3400250-B1 | PROCESS FOR PREPARING GRAFT COPOLYMER COMPRISING POLYETHYLENE | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2022-04-20 | — | — | EP | disclosed |
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |