Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904840 | 0.95 | CCR1 (0.53) | OPRM1ADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL904869 | 0.91 | OPRM1 (0.49) | OPRM1ADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL904903 | 0.90 | ADRA1A (0.55) | OPRM1ADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL904906 | 0.90 | DRD2 (0.48) | OPRM1ADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL904861 | 0.90 | CCR1 (0.61) | OPRM1ADRA1DDRD2ADRA2BADRA2C | |
| SCHEMBL904886 | 0.88 | ADRA1A (0.49) | OPRM1ADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL904868 | 0.88 | DRD2 (0.54) | OPRM1ADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL904842 | 0.86 | OPRM1 (0.54) | OPRM1ADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL12265184 | 0.83 | OPRL1 (0.63) | OPRM1ADRA1AADRA1DADRA1BOPRD1 | |
| SCHEMBL10043044 | 0.83 | OPRM1 (0.57) | OPRM1ADRA1AADRA1DADRA1BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |