Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
| ▸ | HTR1F | P30939 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9044395 | 0.91 | OPRM1 (0.54) | HTR1BDRD2HTR1AHTR2AHTR7 | |
| Oxalic Acid SCHEMBL9050058 | 0.89 | ADRA1D (0.53) | DRD2HTR2AHTR7CCR2ADRA1D | |
| Oxalic Acid SCHEMBL9048375 | 0.88 | MAPT (0.56) | MAPTBLMNPSR1CYP1A2CYP3A4 | |
| SCHEMBL7460711 | 0.80 | CYP1A2 (0.53) | MAPTBLMNPSR1CYP1A2CYP3A4 | |
| SCHEMBL7456066 | 0.79 | CYP1A2 (0.56) | MAPTBLMNPSR1CYP1A2CYP3A4 | |
| SCHEMBL7459131 | 0.79 | CYP1A2 (0.56) | MAPTBLMNPSR1CYP1A2CYP3A4 | |
| SCHEMBL9044439 | 0.79 | ADRA1D (0.46) | HTR1BDRD2HTR1AHTR2AHTR7 | |
| Oxalic Acid SCHEMBL9045241 | 0.78 | HTR1D (0.44) | MAPTBLMNPSR1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL9031120 | 0.77 | CYP1A2 (0.63) | MAPTBLMNPSR1CYP1A2CYP3A4 | |
| Oxalic Acid SCHEMBL9048417 | 0.77 | SLC6A4 (0.55) | DRD2HTR1AHTR2AHTR7CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708102-A1 | 5-HT1F agonists for the treatment of migraine | ELI LILLY AND COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |