Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 4/20 | 0.54 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.54 |
| ▸ | HRH1 | P35367 | 3/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.54 |
| ▸ | HTR6 | P50406 | 3/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MLNR | O43193 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904830 | 0.86 | DRD2 (0.60) | DRD3DRD2HTR2AHTR2CADRA1A | |
| SCHEMBL11563843 | 0.83 | DRD2 (0.46) | DRD2HTR2AHTR2COPRM1HTR6 | |
| SCHEMBL904836 | 0.82 | HTR2A (0.56) | DRD3DRD2HTR2AHTR2CADRA1A | |
| SCHEMBL11567764 | 0.80 | HTR1A (0.54) | DRD3DRD2HTR2AOPRM1OPRK1 | |
| SCHEMBL11563844 | 0.79 | OPRM1 (0.50) | OPRM1OPRK1TSHRCCR5GAA | |
| SCHEMBL11562263 | 0.78 | ACHE (0.54) | DRD3DRD2HTR2AHTR2CHTR1A | |
| SCHEMBL11563880 | 0.78 | CCR5 (0.47) | DRD3DRD2OPRM1HTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL7982489 | 0.77 | DRD2 (0.46) | DRD3DRD2HTR1ASLC6A4KCNH2 | |
| SCHEMBL11567913 | 0.77 | ACHE (0.57) | DRD3DRD2HTR1ASLC6A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL7982494 | 0.76 | DRD2 (0.47) | DRD3DRD2HTR1ASLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |