Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74169 | 0.89 | SLC6A2 (0.47) | SLC6A4SLC6A2SLC6A3LMNAIFNAR1 | |
| SCHEMBL25670209 | 0.83 | SLC6A4 (0.54) | HTR1AHTR3ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL576094 | 0.82 | ACHE (0.53) | HTR1AHTR3AHAO1ARIDO1 | |
| SCHEMBL13579946 | 0.82 | APOBEC3G (0.57) | HTR1AHTR3ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL13272189 | 0.81 | HTR1A (0.41) | HTR1AHTR3ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL21417607 | 0.81 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3LMNAIFNAR1 | |
| SCHEMBL15906499 | 0.79 | HTR1A (0.50) | HTR1AHTR3AHAO1ARIDO1 | |
| Phosphine SCHEMBL29157942 | 0.79 | HTR1A (0.50) | HTR1AHTR3AHAO1ARIDO1 | |
| SCHEMBL29031117 | 0.79 | HTR1A (0.55) | HTR1AHTR3ASLC6A4HAO1AR | |
| Hydrogen Sulfide SCHEMBL11580912 | 0.79 | HTR1A (0.50) | HTR1AHTR3AHAO1ARIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |