Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114300 | 0.90 | CSNK2A2 (0.43) | CSNK2A2CSNK2BCSNK2A1CSNK2A3ADORA2B | |
| SCHEMBL8121668 | 0.82 | ADORA2A (0.46) | ADORA2BNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL8126995 | 0.79 | ADORA2A (0.46) | CSNK2A2CSNK2BCSNK2A1CSNK2A3ADORA2B | |
| SCHEMBL7551424 | 0.79 | CHRNE (0.33) | CSNK2A2CSNK2BCSNK2A1CSNK2A3NPC1 | |
| SCHEMBL3817534 | 0.79 | ACHE (0.34) | NPC1ALDH1A1MAPTRAB9ATHRB | |
| SCHEMBL3176199 | 0.78 | TK1 (0.43) | CSNK2A2CSNK2BCSNK2A1CSNK2A3NPC1 | |
| SCHEMBL3178293 | 0.77 | ALDH1A1 (0.33) | NPC1ALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL14516490 | 0.76 | TLR7 (0.41) | NPC1ALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL3162983 | 0.74 | ALDH1A1 (0.34) | NPC1ALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL4917188 | 0.74 | NPC1 (0.32) | NPC1ALDH1A1MAPTRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708773-A1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002598-A1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-26 | — | — | WO | disclosed |