Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050864 | 0.85 | PTGIR (0.37) | PTGIRSIGMAR1CA1CA2ACHE | |
| SCHEMBL9427081 | 0.84 | PTGIR (0.43) | PTGIRSIGMAR1KDM4C | |
| SCHEMBL9050715 | 0.83 | PTGIR (0.41) | PTGIRSIGMAR1KDM4CACHE | |
| SCHEMBL9427497 | 0.82 | PTGIR (0.48) | PTGIRSIGMAR1KDM4C | |
| SCHEMBL9427328 | 0.81 | SIGMAR1 (0.44) | PTGIRSIGMAR1KDM4CACHE | |
| SCHEMBL9047809 | 0.81 | TBXAS1 (0.43) | PTGIRKDM4C | |
| SCHEMBL9049801 | 0.79 | PTGIR (0.42) | PTGIRSIGMAR1KDM4CACHE | |
| SCHEMBL9048016 | 0.77 | PTGIR (0.48) | PTGIRSIGMAR1KDM4C | |
| SCHEMBL9047483 | 0.77 | ACHE (0.40) | PTGIRSIGMAR1CA1CA2ACHE | |
| SCHEMBL9427217 | 0.76 | PTGIR (0.45) | PTGIRSIGMAR1KDM4CACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |