Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048548 | 0.86 | PTGIR (0.51) | NPSR1ALDH1A1DRD4PDE5APTGIR | |
| SCHEMBL9050555 | 0.82 | NPSR1 (0.47) | NPSR1ALDH1A1PDE5ABDKRB1KCNH2 | |
| SCHEMBL9051667 | 0.79 | PTGIR (0.44) | NPSR1ALDH1A1DRD4PTGIR | |
| SCHEMBL9568017 | 0.78 | KCNQ2 (0.53) | NPSR1ALDH1A1PDE5ATAS1R3TAS1R1 | |
| SCHEMBL9048139 | 0.78 | DRD4 (0.47) | DRD4PTGIR | |
| SCHEMBL9427064 | 0.78 | LMNA (0.45) | DRD4PTGIR | |
| SCHEMBL9048933 | 0.77 | PTGIR (0.52) | DRD4PTGIR | |
| SCHEMBL9048474 | 0.76 | PTGIR (0.36) | DRD4TAS1R3TAS1R1TAS1R2PTGIR | |
| SCHEMBL9046170 | 0.76 | PTGIR (0.44) | DRD4PTGIR | |
| SCHEMBL9048623 | 0.75 | DRD4 (0.49) | DRD4PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |