Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050555 | 0.83 | NPSR1 (0.47) | KCNQ2NPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL9567996 | 0.80 | ALDH1A1 (0.51) | NPSR1HTTALDH1A1MEN1KMT2A | |
| SCHEMBL9269083 | 0.79 | KMT2A (0.62) | KCNQ2HTTCRBNMEN1KMT2A | |
| SCHEMBL9567987 | 0.78 | ALDH1A1 (0.49) | NPSR1HTTALDH1A1MEN1KMT2A | |
| SCHEMBL9050562 | 0.78 | NPSR1 (0.43) | NPSR1ALDH1A1TAS1R3TAS1R1PDE5A | |
| SCHEMBL9048548 | 0.78 | PTGIR (0.51) | NPSR1ALDH1A1KDM4EPDE5A | |
| SCHEMBL3412231 | 0.76 | PRMT5 (0.52) | KCNQ2HTTCRBNALDH1A1MEN1 | |
| SCHEMBL10467510 | 0.76 | PRMT5 (0.52) | KCNQ2HTTCRBNALDH1A1MEN1 | |
| SCHEMBL31613076 | 0.76 | PRMT5 (0.52) | KCNQ2HTTCRBNALDH1A1MEN1 | |
| SCHEMBL10656464 | 0.73 | HTT (0.51) | HTTCRBNALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |