Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049933 | 0.76 | BACE1 (0.37) | BACE1 | |
| SCHEMBL9048432 | 0.70 | — | — | |
| SCHEMBL9048778 | 0.69 | ALOX5 (0.34) | BACE1ALOX5 | |
| SCHEMBL9048433 | 0.69 | — | — | |
| SCHEMBL9048738 | 0.67 | ALOX5 (0.31) | ALOX5 | |
| SCHEMBL9047910 | 0.67 | — | — | |
| SCHEMBL9049169 | 0.67 | — | — | |
| SCHEMBL9049749 | 0.65 | — | — | |
| SCHEMBL9048013 | 0.65 | CHRNA1 (0.33) | — | |
| SCHEMBL9220205 | 0.63 | SLC6A2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555068-B1 | Oxime derivatives as 5-lipoxygenase inhibitors | ZENECA LTD (GB) | 1996-04-10 | — | — | EP | disclosed |
| US-5482966-A | LIPOXYGENASE ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS | ZENECA LIMITED (GB) | 1996-01-09 | — | — | US | disclosed |
| US-5332757-A | Enzyme inhibitors | ZENECA LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |
| EP-0555068-A1 | Oxime derivatives as 5-lipoxygenase inhibitors | ZENECA LIMITED (GB) | 1993-08-11 | — | — | EP | disclosed |